Speaker(s):
Philipp Hendrix, MD, PhD, Attending Neurosurgeon, Geisinger Medical Center & Assistant Professor of Neurosurgery at Geisinger Commonwealth School of Medicine, Geisinger Staff - has nothing to disclose.
Learning Objectives:
At the conclusion of this session, the participant should be able to:
1. Review the major milestones in stroke care, from supportive treatment and alteplase to the 2015 thrombectomy revolution.
2. Explain why mechanical thrombectomy transformed acute stroke treatment, and why newer thrombolytics such as tenecteplase improve but do not replace it.
3. Highlight the next frontier of stroke care, combining precision thrombolysis, better reperfusion strategies, and recovery-focused innovation.
4. Determine the differences between the thrombolytics alteplase (TPA) and tenecteplase (TNK) in acute ischemic stroke.
5. Discuss the trial data that supported U.S. stroke systems’ decision to consider switching from TPA to TNK.
6. Identify the real-world data of TPA vs TNK in large vessel occlusion stroke.
Disclosure of Relevant Financial Relationships with/without Commercial Interests:
The Planning Committee consisting of Candice Laubach, MBA, Christa Martin, PhD, Jennifer Nunamaker, Christian Lynch, MPH, Adam Buchanan, MS, MPH, CGC, and David Rolston, MD, FACP have no identified disclosures.
The Planning Committee member consisting of Eric Wright, PharmD, MPH has identified disclosures: Consultant/Advisor with AstraZeneca.
Any/All relevant financial relationships have been mitigated.
Content Disclosure:
This presentation/content is HIPAA compliant.
Commercial Support for this Session
None
Session date:
06/17/2026 - 12:00pm to 1:00pm EDT
Location:
Virtual via Microsoft Teams
PA
United States
See map: Google Maps
Add to calendar:
- 1.00 ACPE
- 1.00 AMA PRA Category 1 Credit™
- 1.00 Participation Credit

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